Pro-biotic means Pro–life, a feed supplement of microorganisms that beneficially affects the bird's GUT Flora by improving the microbial balance in the intestine, probiotics should be available and stable in different conditions. The most commonly used beneficial probiotics are Bacillus subtillis, licheniformis, megaterium, coagulans, mesentericus, Lacto bacillus spp, Saccharomyces cerevisiae etc.

The micro organism to be considered as probiotics should meet the following requirements,

• It should quickly occupy the intestinal tract.
• It should become part of the intestinal habitat.
• It should be non toxic and non pathogenic, it should survive the action of digestive enzyme and show antagonist action against pathogenic microorganism. Must be stable and viable in commercial preparations.
• Stimulate the immune system.
• Probiotics in diets must increase body weight gain, feed intake, and FCR.
• Promote birds growth and health, especially when conditions are challenging for health.
• The probiotics present in Microsafe work in synergistic and symbiotic manner with each other and makes the product more effective in the GUT.